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Cytarabine / Cytosine Arabinoside

  •  
    IV
    Cytarabine / Cytosine Arabinoside

    • Mechanism of Action
    • Incorporated into DNA, resulting in disruption of DNA synthesis through inhibition of DNA polymerase activity.

Clinical Use

    • Indication
    • Certain haematologic organ malignancies, as guided by cancer specialists and local guidelines.
    • Adverse Effects
    • Bone marrow suppression – anaemia / leukopaenia / thrombocytopaenia
    • Nausea / vomiting / diarrhoea / anorexia
    • Stomatitis / mouth ulcers
    • Elevated LFTs
    • Alopecia
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