- Mechanism of Action
- Directly inhibits the binding of androgens to androgen receptors.
- Interacts with androgen receptors as well as progestin and glucocorticoid receptors, resulting in associated side effects.
- Androgen deprivation therapy for prostate cancer.
- Adverse Effects
- Weight gain
- Nausea / vomiting / diarrhoea
- Gynaecomastia / breast tenderness
- Hot flushes
- Elevated LFTs
- Osteoporosis (long-term)