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Clindamycin

  •  
    Oral / IV
    Clindamycin

    • Mechanism of Action
    • Inhibits protein synthesis by binding to the 50s ribosomal subunit, resulting in inaccurate mRNA translation.
    • Microbiology
    • Effective against staphylococci, streptococci, pneumococci and most anaerobes.

Clinical Use

    • Indications
    • Severe gram positive infections:
    • Upper / lower respiratory tract infections
    • Skin infections
    • Osteomyelitis / septic arthritis
    • Septicaemia
    • Adverse Effects
    • Hypersensitivity reactions
    • Nausea / vomiting / diarrhoea
    • Elevated LFTs

Potential Indications
BETA

Septic Arthritis
Cellulitis
Osteomyelitis
Community-Acquired Pneumonia
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