Drug Guide
 

Clarithromycin

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    Oral
    Clarithromycin
    Biaxin 
    • Mechanism of Action
    • Inhibits protein synthesis by binding to the 50s ribosomal subunit, resulting in inaccurate mRNA translation.
    • Microbiology
    • A wide spectrum of activity against gram positives, atypical respiratory organisms (Legionella, Chlamydia, Mycoplasma) and Bordatella pertussis (whooping cough)

Clinical Use

    • Indications
    • Community-acquired pneumonia (including atypical pneumonia)
    • Mycobacterium avium complex
    • Pertussis (whooping cough)
    • Adverse Effects
    • Nausea / vomiting / diarrhoea
    • Elevated LFTs
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