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Cisatracurium

  •  
    IV
    Cisatracurium
    More potent isomer of atracurium
    Onset 3 minutes
    Duration 40 minutes
    • Mechanism of Action
    • Competitively inhibits the action of acetylcholine on postsynaptic nicotinic receptors, preventing acetylcholine-mediated muscle contraction.

Clinical Use

    • Indications
    • Relaxation of skeletal muscle for anaesthesia during surgery
    • Relaxation of skeletal muscle to facilitate mechanical ventilation in ICU patients
    • Adverse Effects
    • Hypersensitivity reactions – flushing, rash, bronchospasm, anaphylaxis
    • Transient hypotension
    • Tachycardia / bradycardia

Associated Adverse Effects
BETA

Anaphylaxis
Anaphylaxis
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