Cidofovir
- IVCidofovirEmpovir
Mechanism of Action
- Analogues of nucleotides that are incorporated into viral DNA by viral DNA polymerase, resulting in premature DNA termination.
Microbiology
- Active against cytomegalovirus (CMV).
Clinical Use
Indications
- Treatment of CMV retinitis in patients with AIDs.
- Adverse Effects
- Rash
- Headache
- Nausea / vomiting / diarrhoea
- Neutropaenia