Drug Guide
 

Chloroquine

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    Oral
    Chloroquine

    • Mechanism of Action
    • Believed to inhibit haem polymerisation, resulting in a buildup of toxic haem molecules into non-toxic haemozoin within the food vacuole of plasmodia.
    • Microbiology
    • Widespread resistance, therefore rarely used in many countries.

Clinical Use

    • Indications
    • Prevention of malaria
    • Acute Plasmodium malariae or falciparum infection
    • Adverse Effects
    • Nausea / vomiting
    • Elevated LFTs
    • Headache
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