Cetuximab
- IVCetuximabErbitux
- Mechanism of Action
- A monoclonal antibody directed against epidermal growth factor receptor (EGFR / HER1), which is involved in cell signalling and is overexpressed in certain cancers. Inhibition of EGFR signalling pathways results in cell cycle arrest.
Clinical Use
- Indications
- Contraindications
- May not be used in the presence of RAS or BRAF mutations (must be wild type).
- Adverse Effects