MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Drug Guide


    Used for severe infections and for surgical prophylaxis
  • Mechanism of Action
  • A beta lactam antibiotic that inhibits bacterial cell wall synthesis.
  • Broken down by beta lactamase enzymes produced by some bacteria.
  • Microbiology

  • Most effective against gram positive cocci (streptococci and staphylococci), as well as Proteus spp.E coli and Klebsiella spp.

Clinical Use

  • Indications
  • Upper / lower respiratory tract infections
  • Skin infections
  • Urinary tract infections
  • Adverse Effects
  • Very few compared to penicillins.
  • Thrombophlebitis
  • Hypersensitivity reactions
  • Nausea / vomiting / diarrhoea
  • Pseudomembranous colitis (C difficile)
  • Thrombocytopaenia / leukopaenia
  • Nephrotoxicity
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now

Snapshot: Initialising...