Drug Guide
 

Cephalexin

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    Oral
    Cephalexin
    Keflex 
     
    Alternative to fluclox / diclox in patients hypersensitive to penicillins
    • Mechanism of Action
    • Beta lactam antibiotics, which inhibit bacterial cell wall synthesis.

      Broken down by beta lactamase enzymes produced by some bacteria.
    • Microbiology
    • Most effective against gram positive cocci (streptococci and staphylococci), as well as Proteus spp.E coli and Klebsiella spp.

Clinical Use

    • Indications
    • Upper / lower respiratory tract infections
    • Skin infections
    • Urinary tract infections
    • Adverse Effects
    • Very few compared to penicillins.
    • Thrombophlebitis
    • Hypersensitivity reactions
    • Nausea / vomiting / diarrhoea
    • Pseudomembranous colitis (C difficile)
    • Thrombocytopaenia / leukopaenia
    • Nephrotoxicity
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