Drug Guide
 

Celecoxib

Bookmark
  •  
    Oral
    Celecoxib
    Celebrex 
    • Mechanism of Action
    • Inhibits cyclooxygenase, the enzyme responsible for production of thromboxanes, prostacyclin and prostaglandins from arachidonic acid.
    • Pharmacology
    • Selectively binds to COX2, resulting in reduced gastritis / peptic ulceration compared to non-selective NSAIDs.

Clinical Use

    • Indications
    • Pain – including migraine and musculoskeletal injury
    • Fever
    • Inflammation – especially associated with arthritides
    • Prophylaxis (aspirin) – of acute coronary or cerebrovascular events in patients with known cardiovascular or cerebrovascular disease
    • Adverse Effects
    • Gastritis / peptic ulceration
    • Nephrotoxicity
    • Hypertension / fluid retention / congestive cardiac failure / MI
    • Hypersensitivity reactions
    • Delirium
    • Headache
    • Elevated LFTs
    • Neutropaenia
    • Thrombosis
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Explore
   
 
Feedback