×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Ceftriaxone

 
Bookmark
 View Topic Outline
  •  
    IV
    Ceftriaxone

  • Mechanism of Action

  • A beta lactam antibiotic that inhibits bacterial cell wall synthesis.

  • Pharmacology

  • Crosses the blood brain barrier - useful against meningitis.

  • Microbiology

  • More active against gram negative bacteria (Haemophilus, Enterobacteriaciae), less active against gram positive bacteria and inactive against MRSA.

Clinical Use

  • Indications
  • Upper / lower respiratory tract infections
  • Skin infections
  • Urinary tract infections
  • Adverse Effects
  • Very few compared to penicillins.
  • Thrombophlebitis
  • Hypersensitivity reactions
  • Nausea / vomiting / diarrhoea
  • Pseudomembranous colitis (C difficile)
  • Thrombocytopaenia / leukopaenia
  • Nephrotoxicity
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...