Carbimazole

• Mechanism of Action
• Prevents utilization of iodine by the thyroid by inhibiting thyroperoxidase-catalysed iodination of tyrosine residues within the thyroid
  Suspected to have immunosuppressive effects by affecting signaling pathways between thyroid cells and T cells.

Clinical Use

• • Indication
  • Hyperthyroidism, either as a sole agent or prior to surgery / radioiodine.
• • Adverse Effects