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Drug Guide
 
 

Carbamazepine

 
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 View Topic Outline
  •  
    Oral
    Carbamazepine
    Tegretol 

  • Mechanism of Action

  • Inhibits voltage-gated sodium channels, preventing the propagation of action potentials and thus suppressing seizure activity.

Clinical Use

  • Indications
  • Partial (focal) seizures
  • Acute mania
  • Trigeminal neuralgia
  • Adverse Effects
  • CNS disturbances – drowsiness, ataxia, headache, diplopia
  • Nausea / vomiting
  • Rash
  • Anticonvulsant hypersensitivity syndrome (prolonged admin) – fever, rash, lymphadenopathy, hepatitis, myositis
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