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Carbamazepine

  •  
    Oral
    Carbamazepine
    Tegretol 
    • Mechanism of Action
    • Inhibits voltage-gated sodium channels, preventing the propagation of action potentials and thus suppressing seizure activity.

Clinical Use

    • Indications
    • Partial (focal) seizures
    • Acute mania
    • Trigeminal neuralgia
    • Adverse Effects
    • CNS disturbances – drowsiness, ataxia, headache, diplopia
    • Nausea / vomiting
    • Rash
    • Anticonvulsant hypersensitivity syndrome (prolonged admin) – fever, rash, lymphadenopathy, hepatitis, myositis

Potential Indications
BETA

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