Oral
Capecitabine
Xeloda
Converted to 5-fluorouracil once absorbed orally
- Mechanism of Action
- Inhibits thymidylate synthase, resulting in reduced production of dTMP and reduced DNA synthesis.
Clinical Use
- Indication
- Certain solid organ malignancies, as guided by cancer specialists and local guidelines.
- Adverse Effects
- Severe diarrhoea
- Nausea / vomiting
- Alopecia
- Leucopaenia
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