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Capecitabine

  •  
    Oral
    Capecitabine
    Xeloda 
     
    Converted to 5-fluorouracil once absorbed orally
    • Mechanism of Action
    • Inhibits thymidylate synthase, resulting in reduced production of dTMP and reduced DNA synthesis.

Clinical Use

    • Indication
    • Certain solid organ malignancies, as guided by cancer specialists and local guidelines.
    • Adverse Effects
    • Severe diarrhoea
    • Nausea / vomiting
    • Alopecia
    • Leucopaenia
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