Drug Guide
 

Calcitriol

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    Oral
    Calcitriol

    • Mechanism of Action
    • Synthetic 1,25-dihydroxy-vitamin D₃, which stimulates intestinal calcium / phosphate absorption and increased expression of RANK-ligand on osteoblast cell surfaces, resulting in a net increase in serum calcium and phosphate.
    • Pharmacology
    • Significantly more potent than cholecalciferol.

Clinical Use

    • Indications
    • Prevention and treatment of osteoporosis
    • Uraemic osteodystrophy
    • Hypoparathyroidism
    • Rickets
    • Hypocalcaemia
    • Adverse Effects
    • Hypercalcaemia
    • Headache
    • Nausea / abdominal pain
    • Rash
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