MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Drug Guide


    Local / Regional / Epidural
    • Mechanism of Action

    • Binds to and inhibits neuronal voltage-gated sodium channels, suppressing neuronal depolarization and preventing axonal propagation of action potentials.

Clinical Use

    • Indications
    • Procedural anaesthesia – local anaesthesia, nerve block or epidural block
    • Analgesia – local anaesthesia or epidural block
    • Adverse Effects
    • Hypersensitivity reactions – rash, oedema, anaphylaxis
    • Inadvertent IV administration – agitation, drowsiness, bradycardia, hypotension, ventricular arrhythmia, hyperkalaemia, hypoxia
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now