Oral
Bisoprolol
Bicor
Used to treat stable heart failure only
- Mechanism of Action
- Competitively inhibit the action of adrenaline and noradrenaline on β1 receptors (the predominant β receptors in the heart), resulting in suppression of the sympathetic nervous system with negative inotropy, chronotropy, dromotropy and lusiotropy.
Clinical Use
- Indication
- Stable heart failure
- Contraindications
- Asthma
- Decompensated heart failure
- AV block
- Adverse Effects
- Fatigue / headache
- Bradycardia
- Postural hypotension
- Nausea / vomiting / diarrhoea
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