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Basiliximab

  •  
    IV
    Basiliximab
    Simulect 
    • Mechanism of Action
    • A mouse / human chimaeric monoclonal antibody that binds and inhibits IL-2 receptors (CD-25) on activated T cells, resulting in reduced T cell proliferation.

Clinical Use

    • Indication
    • Prevention of acute renal transplant rejection.
    • Adverse Effects
    • Does not appear to significantly add to the adverse events already seen in transplant patients due to underlying disease or immunosuppressant medications.
    • Infections
    • Headache
    • Hypertension
    • Nausea / vomiting / diarrhoea / constipation

Associated Adverse Effects
BETA

Secondary Hypertension
Secondary Hypertension
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