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Drug Guide
 
 

Basiliximab

 
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  •  
    IV
    Basiliximab
    Simulect 

  • Mechanism of Action

  • A mouse / human chimaeric monoclonal antibody that binds and inhibits IL-2 receptors (CD-25) on activated T cells, resulting in reduced T cell proliferation.

Clinical Use

  • Indications

  • Prevention of acute renal transplant rejection.
  • Adverse Effects
  • Does not appear to significantly add to the adverse events already seen in transplant patients due to underlying disease or immunosuppressant medications.
  • Infections
  • Headache
  • Hypertension
  • Nausea / vomiting / diarrhoea / constipation
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