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Baricitinib

  •  
    Oral
    Baricitinib
    Olumiant 
     
    Selective inhibitor of JAK1 and JAK2
    • Mechanism of Action
    • Inhibits Janus Kinases (JAK1 and JAK2), a group of non-receptor tyrosine kinases involved in signalling downstream to cytokine receptors in immune and haematopoietic cells.

Clinical Use

    • Indication
    • Moderate to severe rheumatoid arthritis refractory to methotrexate.
    • Adverse Effects
    • Severe infections (particularly respiratory and urinary tract infections)
    • Anaemia
    • Headache
    • Dizziness
    • Nausea / vomiting / diarrhoea
    • Hypertension
    • Hypercholesterolaemia
    • Abdominal pain

Potential Indications
BETA

Associated Adverse Effects
BETA

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