×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Baricitinib

 
Bookmark
  •  
    Oral
    Baricitinib
    Olumiant 
     
    Selective inhibitor of JAK1 and JAK2
  • Mechanism of Action

  • Inhibits Janus Kinases (JAK1 and JAK2), a group of non-receptor tyrosine kinases involved in signalling downstream to cytokine receptors in immune and haematopoietic cells.

Clinical Use

  • Indications

  • Moderate to severe rheumatoid arthritis refractory to methotrexate.
  • Adverse Effects
  • Severe infections (particularly respiratory and urinary tract infections)
  • Anaemia
  • Headache
  • Dizziness
  • Nausea / vomiting / diarrhoea
  • Hypertension
  • Hypercholesterolaemia
  • Abdominal pain
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now