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Baclofen

  •  
    Oral / Intrathecal
    Baclofen

    • Mechanism of Action
    • A GABA analogue that agonises GABAB receptors.

Clinical Use

    • Indications
    • Suppression of muscle spasm due to multiple sclerosis
    • Suppression of muscle spasm due to spinal lesions such as trauma, infection, degenerative change or neoplasia, with associated hypertonicity.
    • Adverse Effects
    • Nausea / vomiting
    • Drowsiness
    • Myalgia / muscle weakness
    • Tinnitus
    • Visual changes
    • Hypotension
    • Rash
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