Oral / Intrathecal
Baclofen
- Mechanism of Action
- A GABA analogue that agonises GABAB receptors.
Clinical Use
- Indications
- Suppression of muscle spasm due to multiple sclerosis
- Suppression of muscle spasm due to spinal lesions such as trauma, infection, degenerative change or neoplasia, with associated hypertonicity.
- Adverse Effects
- Nausea / vomiting
- Drowsiness
- Myalgia / muscle weakness
- Tinnitus
- Visual changes
- Hypotension
- Rash
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