- Oral / IntrathecalBaclofen
Mechanism of Action
- A GABA analogue that agonises GABAB receptors.
- Suppression of muscle spasm due to multiple sclerosis
- Suppression of muscle spasm due to spinal lesions such as trauma, infection, degenerative change or neoplasia, with associated hypertonicity.
- Adverse Effects
- Nausea / vomiting
- Myalgia / muscle weakness
- Visual changes