Azithromycin

• Mechanism of Action
• Inhibits protein synthesis by binding to the 50s ribosomal subunit, resulting in inaccurate mRNA translation.
• • Microbiology
  • A wide spectrum of activity against gram positives, atypical respiratory organisms (Legionella, Chlamydia, Mycoplasma) and Bordatella pertussis (whooping cough)

Clinical Use

• • Indications
  • Community-acquired pneumonia (including atypical pneumonia)
  • Chlamydia
  • Pertussis (whooping cough)
• • Adverse Effects
  • Nausea / vomiting / diarrhoea
  • Elevated LFTs