Aspirin + Dipyridamole
- OralAspirin + DipyridamoleAsasantin
- Mechanism of Action
- Aspirin inhibits cyclooxygenase, the enzyme responsible for production of thromboxanes, prostacyclin and prostaglandins from arachidonic acid.
Dypyridamole inhibits platelet cAMP-phosphodiesterase, preventing platelet aggregation. Also augments the platelet inhibitory effect of adenosine by preventing reuptake and degradation of adenosine by endothelial and red blood cells.
- Adverse Effects