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Anti-Thymocyte Globulin

 
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    IV
    Anti-Thymocyte Globulin
    Thymoglobuline 

  • Mechanism of Action

  • Rabbit immunoglobulin directed mainly against T cells that causes rapid central and peripheral lymphocyte depletion.

Clinical Use

  • Indications
  • Prevention of graft rejection in renal transplantation
  • Treatment of renal transplant rejection
  • Refractory or relapsing aplastic anaemia
  • Adverse Effects
  • Fevers (ocur without infection in the majority of patients)
  • Rash
  • Arthralgias / myalgias
  • Nausea / vomiting / diarrhoea
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