MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Drug Guide

Amphotericin B Lipid Complex

    Amphotericin B Lipid Complex
    Less toxicity due to direct fungal cell binding
  • Mechanism of Action

  • Binds to ergosterol on the cell membrane, resulting in the formation of pores, leakage of cytoplasmic components and cell death.
  • Microbiology

  • Effective against Candida, Cryptococcus and Aspergillus.

Clinical Use

  • Indications
  • Invasive candidiasis
  • Cryptococcal meningitis
  • Aspergillosis
  • Adverse Effects
  • Infusion reactions - fevers, rigors, arthralgias, hypotension, bronchospasm
  • Nephrotoxicity
  • Anaemia
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now

Snapshot: Initialising...