Amphotericin B
- IVAmphotericin B
- Mechanism of Action
- Binds to ergosterol on the cell membrane, resulting in the formation of pores, leakage of cytoplasmic components and cell death.
- Microbiology
- Effective against Candida, Cryptococcus and Aspergillus.
Clinical Use
- Indication
- Systemic candidiasis, cryptococcal meningitis, aspergillosis
- Adverse Effects