Amoxicillin

• Mechanism of Action
• A beta lactam antibiotic that inhibits bacterial cell wall synthesis.
• • Microbiology
  • More active than narrow spectrum penicillins against certain gram negatives, such as E coli and Haemophilus influenzae.

Clinical Use

• • Indications
  • Community-acquired pneumonia
  • Peritonsillar abscess
  • Bacterial endocarditis
  • Rheumatic fever
  • Syphilis
• • Adverse Effects
  • Hypersensitivity - urticarial rash, oedema, anaphylaxis
  • GIT - nausea / vomiting / diarrhoea
  • Thrombocytopaenia / leukopaenia