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Drug Guide
 
 

Amlodipine

 
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    Oral
    Amlodipine
    Amlo, Norvasc 
  • Mechanism of Action

  • Inhibits L-type calcium channels on ventricular myocardial, cardiac nodal and arteriolar smooth muscle cells.
  • Pharmacology

  • Selectively inhibits calcium channels on arteriolar smooth muscle cells, resulting in significant vasodilation without cardiodepression.

Clinical Use

  • Indications
  • Hypertension - first line treatment
  • Stable angina pectoris
  • Contraindications

  • Heart failure.
  • Adverse Effects
  • Fatigue
  • Oedema
  • Dizziness
  • Headache
  • Nausea / abdo pain
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