Amitriptyline | Drug Guide - MedSchool
Sign up to start your free trial of MedSchool Premium!Get Started
 
Drug Guide
 
 
#
A
B
C
D
E
F
G
H
I
K
L
M
N
O
P
Q
R
S
T
U
V
W
Z
 

Amitriptyline

Bookmark
  •  
    Oral
    Amitriptyline
    Endep 
    • Mechanism of Action
    • Blocks presynaptic reuptake of serotonin (5-HT) and noradrenaline (NA) through an unknown mechanism.

Clinical Use

    • Indications
    • Depression
    • Fibromyalgia
    • Migraine prophylaxis
    • Neuropathic pain
    • Post-traumatic stress disorder (PTSD)
    • Contraindications
    • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
    • Adverse Effects
    • Nausea / vomiting / diarrhea
    • Adrenergic – postural hypotension
    • Histaminic – sedation, weight gain
    • Anticholinergic - dry mouth, blurred vision, constipation, urinary retention
 
Feedback