Oral
Allopurinol
Zyloprim, Progout
May be associated with increased cardiovascular risk
- Mechanism of Action
- Inhibits xanthine oxidase, which normally produces uric acid through oxidation of xanthine and hypoxanthine.
Clinical Use
- Indications
- Gout - acute gouty arthritis, reduction in gouty tophi
- Tumour lysis syndrome
- Adverse Effects
- Headache
- Nausea / vomiting / diarrhoea
- Hypersensitivity reactions
- Rash
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