Adenosine
- IVAdenosine
Mechanism of Action
- A naturally ocurring purine nucleoside that supresses the sinoatrial node, shortens phase 2 of the cardiomyocyte action potential and supresses AV nodal conduction through effects on potassium and calcium currents.
Clinical Use
- Indications
- Acute management of paroxysmal supraventricular tachycardia
- Diagnosis of supraventricular tachycardia
- Adverse Effects
- Bradyarrhythmias - bradycardia, heart block
- Dyspnoea
- Headache
- Lightheadedness
- Nausea
- Chest pain