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Drug Guide
 
 

Adenosine

 
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    Adenosine

  • Mechanism of Action

  • A naturally ocurring purine nucleoside that supresses the sinoatrial node, shortens phase 2 of the cardiomyocyte action potential and supresses AV nodal conduction through effects on potassium and calcium currents.

Clinical Use

  • Indications
  • Acute management of paroxysmal supraventricular tachycardia
  • Diagnosis of supraventricular tachycardia
  • Adverse Effects
  • Bradyarrhythmias – bradycardia, heart block
  • Dyspnoea
  • Headache
  • Lightheadedness
  • Nausea
  • Chest pain
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