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Adenosine

  •  
    IV
    Adenosine

    • Mechanism of Action
    • A naturally ocurring purine nucleoside that supresses the sinoatrial node, shortens phase 2 of the cardiomyocyte action potential and supresses AV nodal conduction through effects on potassium and calcium currents.

Clinical Use

    • Indications
    • Acute management of paroxysmal supraventricular tachycardia
    • Diagnosis of supraventricular tachycardia
    • Adverse Effects
    • Bradyarrhythmias – bradycardia, heart block
    • Dyspnoea
    • Headache
    • Lightheadedness
    • Nausea
    • Chest pain

Potential Indications
BETA

Focal Atrial Tachycardia
Multifocal Atrial Tachycardia
AV Nodal Reentrant Tachycardia
AV Reentrant Tachycardia

Associated Adverse Effects
BETA

Atrioventricular Block
Atrioventricular Block
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