- Oral / IVAciclovirHerpex, zovirex20% bioavailability; mainly used for HSV and VZV
- Mechanism of Action
- A nucleoside analogue that is incorporated into viral DNA by viral DNA polymerase, resulting in premature DNA termination.
- Effective against Herpes simplex virus (HSV), varicella zoster virus (VZV) and cytomegalovirus (CMV), though impossible to reach therapeutic levels sufficient to be effective against CMV.
- Adverse Effects
- Nausea / vomiting, headache.