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Drug Guide
 
 

Abiraterone

 
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  •  
    Oral
    Abiraterone
    Zytiga 

  • Mechanism of Action

  • Inhibits 17-α hydroxylase / C17,20-lyase (CYP17) which is expressed in prostatic tumour tissue and is required for androgen synthesis.

Clinical Use

  • Indications

  • Metastatic prostate cancer.
  • Adverse Effects
  • Fatigue
  • Hot flushes
  • Hypokalaemia
  • Hypertension
  • Peripheral oedema
  • LFT derangement
  • Diarrhoea
  • Anaemia
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