Drug Guide
 

Abiraterone

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    Oral
    Abiraterone
    Zytiga 
    • Mechanism of Action
    • Inhibits 17-α hydroxylase / C17,20-lyase (CYP17) which is expressed in prostatic tumour tissue and is required for androgen synthesis.

Clinical Use

    • Indication
    • Metastatic prostate cancer.
    • Adverse Effects
    • Fatigue
    • Hot flushes
    • Hypokalaemia
    • Hypertension
    • Peripheral oedema
    • LFT derangement
    • Diarrhoea
    • Anaemia
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