- IV / SubcutAbataceptOrencia
- Mechanism of Action
- A fusion protein with the Fc fragment of human IgG1 linked to the extracellular domain of CTLA-4. Binds to CD80 / CD86 on antigen presenting cells and prevents binding by CD28 on T lymphocytes, resulting in lack of a costimulatory response and reduced T cell activation.
- Not to be used concurrently with other biologic DMARDs.
- Adverse Effects