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Tuberculosis
 
Tuberculosis
 

Respiratory Tuberculosis

 
 
 
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Overview

Tuberculosis is the disease caused by the bacteria Mycobacterium tuberculosis, and may affect almost any organ in the body resulting in a wide range of clinical presentations.

Pathogenesis

  • Risk Factors for Tuberculosis

  • Immunosuppression - HIV, post transplant, autoimmune disease
  • Alcohol abuse
  • Malnutrition
  • Diabetes
  • Smoking

Management

  • Management Options

  • Latent TB

  • Isoniazid
  • Rifampicin
  • Active TB

  • First line (HRZE) - isoniazid, rifampicin, pyrazinamide and ethambutol
  • Other options - amikacin, capreomucin, moxifloxacin, linezolid, cycloserine, clofazimine, meropenem, augmentin
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