×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Metabolic Disorders
 
 

Secondary Hyperlipidaemia

 
Bookmark

Pathogenesis

    • Causes of Hyperlipidaemia

    • Primary

    • Familial lipoprotein lipase deficiency
    • Familial hypercholestolaemia
    • Familial combined hyperlipidaemia
    • Familial dysbetalipoproteinaemia
    • Familial hypertriglyceridaemia
    • Secondary: Predominantly LDL

    • Hypothyroidism
    • Cholestatic liver disease
    • Nephrotic syndrome
    • Secondary: Predominantly TAGs

    • Obesity
    • Diabetes
    • Alcohol abuse
    • Chronic kidney disease
    • Drugs - corticosteroids, antipsychotics, immunosuppressants, protease inhibitors, oral contraceptive pill, hormone replacement therapy
    • Pregnancy

Manifestations

    • Complications of Hyperlipidaemia

    • Atherosclerosis

    • Ischaemic heart disease
    • Ischaemic stroke
    • Erectile dysfunction
    • Peripheral vascular disease
    • Other

    • Non-alcoholic fatty liver disease

Management

    • Management Options

    • Non-Pharmacologic

    • Dietary changes
    • Fish oil supplementation
    • Exercise
    • Alcohol avoidance
    • Smoking cessation
    • Pharmacologic

    • Statins - atorvastatin, pravastatin, rosuvastatin, simvastatin
    • Fibrates - fenofibrate, gemfibrozil
    • Ezetimibe
    • PCSK-9 inhibitors - alirocumab
 
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now