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Electrolyte Abnormalities
Electrolyte Abnormalities

Metabolic Acidosis



Metabolic acidosis is a process in which an external agent or internal process is causing excessive acidity in a way that is metabolic (i.e. non-respiratory).


  • Causes of Metabolic Acidosis

  • High Anion Gap Metabolic Acidosis

  • Lactic acidosis
  • Ketoacidosis - diabetic, alcoholic
  • Uraemia (end-stage renal failure)
  • Methanol / ethanol / ethylene glycol
  • Salicylates
  • Cyanide
  • Carbon monoxide
  • Normal Anion Gap Metabolic Acidosis


  • Blood Gas Findings

  • Acidaemia with reduced bicarbonate.
  • Approach

  • Check the anion gap to further distinguish between causes.
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