Overview
Sick sinus syndrome (SSS) occurs when the sinus node is not functioning correctly, due to either intrinsic or extrinsic causes.
Pathogenesis
Causes of Sinus Node Dysfunction
- Idiopathic degeneration
- Myocardial infarction
- Infiltrative disease - sarcoidosis, amyloidosis, haemochromatosis
- Connective tissue disease - SLE, scleroderma, RA
- Cardiac surgery - valvular surgery, correction of congenital heart disease
- Infections - Lyme disease, endocarditis
Manifestations
Manifestations of Sinus Node Dysfunction
- Sinus bradycardia
- Sinus arrhythmia
- Sinus pause / arrest
- Sinoatrial exit block
- Tachy-brady syndrome
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