Pleural Fluid Analysis Bookmark ShareAnalysis of a pleural fluid sample is performed to assist in diagnosing the cause of a pleural effusion. Tests performed may include biochemistry, cell counts, cytology and culture. Intercostal Catheter Insertion***Causes of pleural effusionRoutine TestsAppearanceClear, blood-stained, milky, bilious, blackLight's CriteriaPleural fluid : serum protein / LDHFluid : Serum Protein >0.5Fluid : Serum LDH >0.6Fluid LDH >⅔ ULNGlucoseLow glucose suggestive of infection, inflammation, malignancyCell CountWhite & red blood cellsOther TestsAmylaseIf concern for pancreatitisAdenosine Deaminase (ADA)Elevation weakly suggestive of TBTriglycerides>110mg/dL is indicative of chylothoraxNT-ProBNPHighly sensitive & specific for heart failureFluid CultureTo identify bacterial organismAcid-Fast BacilliIf TB pleuritis suspectedCytologySensitivity ~60%May yield a diagnosis of malignancyOn this page: Routine TestsOther Tests