Neuro History
 

The Epilepsy History

 
 
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Overview

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    • Diagnosis - when diagnosed, EEG changes, MRI changes
    • Family history of seizures / epilepsy
    • Manifestations - type of seizures, prodrome, postictal period
    • Severity - frequency of seizures, last seizure
    • Management - avoidance of precipitants, medications
    • Causes of Epilepsy

    • Genetic
    • Trauma - open or closed head injury, neurosurgery
    • Cerebrovascular - haemorrhage, ischaemia, arteriovenous malformation
    • Malignancy - glioma, meningioma, metastasis
    • CNS infection - meningitis, encephalitis, malaria, tuberculosis
    • Autoimmune - systemic lupus erythematosus
    • Degeneration - Alzheimer’s, multiple sclerosis
    • Idiopathic
    • Potential Precipitants of Seizures

    • Sleep deprivation
    • Fatigue
    • Fasting
    • Drugs
    • Alcohol
    • Flashing lights
    • Fever
    • Stress
    • Menstruation
    • Missed antiepileptic dosing
    • Epilepsy Syndromes

    • Neonatal / Infantile

    • Ohtahara syndrome
    • West syndrome
    • Doose syndrome
    • Dravet syndrome
    • Myoclonic epilepsy of infancy
    • Childhood

    • Lennox-Gastaut syndrome
    • Childhood absence epilepsy
    • Benign Rolandic epilepsy
    • Adolescence / Adulthood

    • Juvenile absence epilepsy
    • Juvenule myoclonic epilepsy
    • Temporal lobe epilepsy

Management

    • Management Options for Epilepsy

    • Non-Pharmacologic

    • Avoidance of precipitants
    • Avoidance of driving (consult local guidelines)
    • Pharmacologic

    • Carbamazepine
    • Phenytoin
    • Sodium valproate
    • Topiramate
    • Levetiracetam
    • Lamotrigine
    • Lacosamide
    • Ethosuxamide
    • Benzodiazepines
    • Invasive Options

    • Surgical resection of an epileptogenic lesion
    • Vagus nerve stimulation
    • Deep brain stimulation
Last updated on July 6th, 2019
 
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