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Psych Drugs
 
 

Antidepressants

Antipsychotics

Anxiolytics

Mood Stabilisers

Drugs of Abuse

Medications for Substance Abuse

 
 

Selective Serotonin Reuptake Inhibitors

 
 
  •  
    Oral
    Citalopram
    Cipramil, Celexa 
     
    First line agent for depression
  •  
    Oral
    Escitalopram
    Lexapro 
  •  
    Oral
    Fluoxetine
    Prozac, Lovan 
  •  
    Oral
    Fluvoxamine
    Luvox 
  •  
    Oral
    Paroxetine
    Aropax, Paxil 
  •  
    Oral
    Sertraline
    Zoloft 

Overview

    • Mechanism of Action

    • Selectively inhibit the presynaptic serotonin (5-HT) transporter, resulting in reduced reuptake of serotonin and greater serotonin concentrations within the synapse.

Clinical Use

    • Indications

    • Depression
    • Obsessive-compulsive disorder
    • Generalised anxiety disorder
    • Panic disorder (paroxetine / sertraline)
    • Post-traumatic stress disorder (paroxetine / sertraline)
    • Contraindication

    • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
    • Adverse Effects

    • Insomnia
    • Drowsiness
    • Agitation
    • Dry mouth
    • Headache
    • Weight gain / loss
    • Nausea / vomiting / diarrhoea
    • Sexual dysfunction – decreased libido, ejaculatory disorders, erectile dysfunction
    • Serotonin syndrome (when SSRIs given with MAOis / SNRIs) – confusion, agitation, ataxia, hyperreflexia, fevers, diaphoresis
 
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The information in this section has been adapted in part from the Australian Therapeutic Goods Association website's repository of product information documents, which are available at https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/PICMI.
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