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Gastro Drugs
 
 

Antiemetics

Gastric Secretion Modulators

Laxatives

Inflammatory Bowel Disease Medications

 
 

Antidopaminergics

 
 
  •  
    Oral / IM / IV
    Metoclopramide
    Maxolon, Pramin 
     
    Selectively binds D2 receptors
  •  
    Oral
    Domperidone
    Motilium 
     
    Binds D2 and D3 receptors; doesn’t cross the BBB
  •  

Overview

    • Mechanism of Action

    • Antagonise CNS dopamine receptors, resulting in reduction in nausea and increased upper GI motility.

Clinical Use

    • Indications

    • Nausea / vomiting
    • Gastroparesis
    • Adverse Effects

    • Restlessness / anxiety / agitation
    • Fatigue
    • Headache / dizziness
    • Diarrhoea
    • Dystonic reactions (rare)
 
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The information in this section has been adapted in part from the Australian Therapeutic Goods Association website's repository of product information documents, which are available at https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/PICMI.
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