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Endocrine Drugs
 
 
 

Sulfonylureas

 
 
  •  
    Oral
    Gliclazide
    Diamicron 
  •  
    Oral
    Glimepiride
    Amaryl 
  •  
    Oral
    Glipizide
    Melizide 

Overview

    • Mechanism of Action

    • Inhibit potassium channels on pancreatic beta cell membranes, resulting in calcium influx and thus insulin release.

Clinical Use

    • Indication

    • Second line agent for glycaemic control in type II diabetes.
    • Adverse Effects

    • Hypoglycaemia
    • Nausea / vomiting / diarrhea
    • Thrombocytopaenia / leukopaenia / haemolytic anaemia
    • Weight gain
Last updated on January 1st, 2017
 
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The information in this section has been adapted in part from the Australian Therapeutic Goods Association website's repository of product information documents, which are available at https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/PICMI.
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