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Emergency Drugs
 
 
 

Fomepizole

 
 
  •  
    IV
    Fomepizole
    Antizol 

Overview

    • Mechanism of Action

    • Directly inhibits ADH, which metabolizes methanol and ethylene glycol into toxic metabolites formic acid and glycolic acid respectively.
    • Pharmacology

    • Higher affinity for ADH than ethanol.

Clinical Use

    • Indication

    • Methanol or ethylene glycol poisoning.
    • Adverse Effects

    • Headache
    • Nausea / vomiting
    • Dizziness
    • Drowsiness
    • Metallic taste
Last updated on August 18th, 2018
 
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