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Blood Products
 
 
Blood Products
Human blood products including red blood cells, platelets and plasma products are provided as transfusions for a variety of therapeutic indications. They are associated with potential adverse effects of which it is important to be aware.
 

Platelets

 
 
  •  
    IV
    Apheresis Platelets
    Blood is removed, platelets collected and blood returned to patient
  •  
    IV
    Pooled Platelets
    Equivalent to 5 units of apheresis platelets
  •  
    IV
    Phenotyped Platelets
    For patients with clinically significant antibodies – lack specific antigens
  •  
    IV
    Irradiated Platelets
    Lack T cells, which normally mediate transfusion-related graft-vs-host disease – for use in transplant and severely immunosuppressed patients
  •  
    IV
    CMV Seronegative Platelets
    Tested and cleared of CMV, for use in severely immunosuppressed patients

Overview

  • Human platelets are used to treat patients with thrombocytopaenia due to a variety of causes.
    • Composition

    • Platelets
    • Additive solution - sodium chloride, sodium acetate, sodium citrate, sodium dihydrogenophosphate, disodium hydrogenophosphate, potassium chloride, magnesium chloride

Clinical Use

  • Consult local guidelines regarding the use of blood products in your area.
    • Indications

    • Non-bleeding patients: platelet count <10
    • Major surgery: platelet count <50
    • Ocular / neurosurgery: platelet count <100
    • Defective platelet function
    • Contraindications

    • Thrombotic thrombocytopaenic purpura (TTP)
    • Heparin-induced thrombocytopaenia (HIT)
  • One unit of pooled platelets is expected to increase the serum platelet count by 30-50.
Last updated on January 17th, 2019
 
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