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Blood Products
 
 
 
 
Blood Products
Human blood products including red blood cells, platelets and plasma products are provided as transfusions for a variety of therapeutic indications. They are associated with potential adverse effects of which it is important to be aware.
 

Fresh Frozen Plasma

 
 
  •  
    IV
    Whole Blood Plasma
    Plasma separated from whole blood collection
  •  
    IV
    Apheresis Plasma
    Blood is removed, plasma collected and blood returned to patient
  •  
    IV
    IgA-Deficient Plasma
    Tested for IgA, for use in IgA-deficient patients who may have developed anti-IgA antibodies.
  •  
    IV
    Low Titre Anti-T Plasma
    Tested for anti-T, for use in patients at risk of haemolytic reactions
  •  
    IV
    Donor Secretor Plasma
    For use prior to bone marrow transplant with major ABO mismatch, in order to reduce the risk of haemolysis and pure red cell aplasia

Overview

  • Fresh frozen plasma (FFP) is a blood product made up of the plasma portion of whole blood, following removal of all cells.
    • Composition

    • Proteins - albumin, (immuno)globulins, fibrinogen
    • Coagulation factors
    • Carbohydrates
    • Lipids
    • Electrolytes
    • Hormones

Clinical Use

    • Indications

    • INR >1.6 in patients not on warfarin
    • Warfarin reversal – major haemorrhage, emergent presurgical
    • Disseminated intravascular coagulation (DIC)
    • Massive transfusion
Last updated on January 17th, 2019
 
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