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Blood Products
 
 
 
 
Blood Products
Human blood products including red blood cells, platelets and plasma products are provided as transfusions for a variety of therapeutic indications. They are associated with potential adverse effects of which it is important to be aware.
 

Cryoprecipitate

 
 
  •  
    IV
    Whole Blood Cryoprecipitate
    Plasma separated from whole blood collection and then cryoprecipitate isolated from plasma
  •  
    IV
    Apheresis Cryoprecipitate
    Blood is removed, plasma collected, blood returned to patient and then cryoprecipitate is isolated from plasma

Overview

  • In order to create cryoprecipitate, fresh frozen plasma is thawed to between 1-6°C and the precipitate is collected. This creates a product that is richer in fibrinogen than FFP.
    • Composition

    • Factor VIII
    • Fibrinogen
    • Factor XIII
    • Von Willebrand factor
    • Fibronectin

Clinical Use

    • Indications

    • Massive transfusion
    • Large haemorrhage during surgery
  • Each unit of cryoprecipitate is expected to increase the serum fibrinogen by 5-10mg/dL.
Last updated on January 17th, 2019
 
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