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Antifungals
 
 
 

Triazoles

 
 
  •  
    Oral / IV
    Fluconazole
    Diflucan 
  •  
    Oral
    Itraconazole
    Cover against years and moulds
  •  
    Oral / IV
    Voriconazole
    Vfend 
     
    Activity against moulds, including Aspergillus

Overview

    • Mechanism of Action

    • Inhibit fungal synthesis of ergosterol, an element of the fungal cell membrane.
    • Microbiology

    • Effective against Cryptococcus and Candida. Voriconazole is also effective against moulds, including Aspergillus.

Clinical Use

    • Indications

    • Cryptococcal meningitis
    • Invasive candidiasis
    • Aspergillosis (voriconazole)
    • Adverse Effects

    • Rash
    • Nausea / vomiting / diarrhoea
Last updated on August 17th, 2018
 
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