Login or Register to unlock everything MedSchool has to offer!
Antifungals
 
 
 

Echinocandins

 
 
  •  
    IV
    Caspofungin

  •  
    IV
    Anidulafungin
    Eraxis 
     
    No liver metabolism - can be used in patients with liver failure

Overview

    • Mechanism of Action

    • Inhibit synthesis of beta (1,3)-D-glucan, an essential component of the fungal / yeast cell wall.
    • Microbiology

    • Effective against invasive candidiasis and invasive aspergillosis.

Clinical Use

    • Indications

    • Febrile neutropaenia with suspected fungal source
    • Invasive candidiasis
    • Refractory invasive aspergillosis
    • Adverse Effects

    • Hypersensitivity reactions
    • Nausea / vomiting / diarrhoea
    • Headache
Last updated on August 17th, 2018
 
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Feedback