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    Oral / IV
    Oral / IV
    Useful for pneumonia in patients with severe penicillin / cephalosporin allergy, due to Staph and atypical cover


    • Mechanism of Action

    • Inhibit DNA gyrase, preventing supercoiling of DNA and disrupting cell division.
    • Microbiology

    • Broad spectrum of activity against most gram negatives including Pseudomonas

Clinical Use

    • Indications

    • Gastroenteritis (empirical agents of choice)
    • Genitourinary infections - UTI, PID, bacterial prostatitis
    • Skin infections
    • Osteomyelitis / septic arthritis
    • Anthracosis
    • Adverse Effects

    • Nausea, vomiting, diarrhoea
    • Headache / dizziness / fatigue
    • QT prolongation
    • Tendinopathy (in children)
Last updated on August 11th, 2018


The information in this section has been adapted in part from the Australian Therapeutic Goods Association website's repository of product information documents, which are available at https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/PICMI.
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